Role of Probiotics in Animal Nutrition Probiotics are live cultures of microorganisms including species of Lactobacillus, Bifidobacterium, yeasts etc, that beneficially affect the host upon ingestion by improving the balance of the intestinal microflora. The gastrointestinal tract is a complex ecosystem in which a delicate balance exists between the intestinal microflora and the host. The microflora is principally comprised of Facultative anaerobes (Lactobacillus, Escherichia coli, Klebsiella, Streptococcus, Staphylococcus and Bacillus) and obligate anaerobes (Bifidobacterium, Clostridium, Eubacterium, Fusobacterium, Bacteroides). The intestinal microflora primarily acts as a barrier of intestinal mucosa thereby preventing the colonization of pathogenic microorganisms and entry of allergens. They are also known to produce certain antibiotic like substances which help control the pathogenic microorganisms. Intestinal microflora also helps maturation of the immune system, development of normal intestinal morphology and in immunologic ally balanced inflammatory response. Some of the microflora are also known to contribute to the body?s requirements of certain vitamins, biotin, pantothenic acid and Vitamin B12. The balance of microbial flora may get disturbed due to use of antibiotics or chemotherapeutics, ageing, disease, stress, etc. Probiotics are popular on a commercial scale in animal feeds as alone and along with yeasts, and fungal cultures producing fiber degrading enzymes. Their use in pelleted feed has been limited because most of the strains of probiotic bacterial cultures were destroyed at pelleting temperatures. Research has shown that probiotic cultures performed significantly better in improving livestock performance when they were supplemented with specific nutrients. Also, no adverse or toxic reactions have so far been reported with the use of probiotics in animal feed. This product has been developed especially for Mouse and Rat to be used in large farms, or by pet owners. PRO-VITAL’S Mouse and Rat formula is complete, developed for high producing animals or to maintain optimum health including in the aid and control of many ailments. Our formula contains: 1. Probiotics different strains A. boost immunity B. produce digestive enzymes 2.Vitamins, complete spectrum 3. Minerals, chelated for easy absorption and positive effect. 4. Malto Dextrin as a fast energy source 5. PRO-VITAL’S Bio-Tag, used in the prevention of disease 6. Pro-Vital’s Odor-gone as a fecal odor eliminator. 7 Digestive enzymes, for easy and efficient digestion of food stuff 8. Can be given in the water or mixed in the food.